Tg(KRT14-HPV16E5*)33Plam
Transgene Detail

Summary

• Symbol: Tg(KRT14-HPV16E5*)33Plam
• Name: transgene insertion 33, Paul F Lambert
• MGI ID: MGI:7261144
• Synonyms: HPV16 AU-1E5*, Tg(KRT14-HPV16AU1E5*)33Plam
• Transgene: Tg(KRT14-HPV16E5*)33Plam Location: unknown
• Alliance: Tg(KRT14-HPV16E5*)33Plam page

Transgene origin

• Strain of Origin: FVB/NTac

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: The human promoter drives basal layer-specific expression of an HPV16 fragment containing the codon optimized sequence encoding the E5 protein with an N-terminal 6 amino acid tag (AU1). Like 33 contains 10 copies of the transgene. (J:100781)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:100781 Genther Williams SM, et al., Requirement of epidermal growth factor receptor for hyperplasia induced by E5, a high-risk human papillomavirus oncogene. Cancer Res. 2005 Aug 1;65(15):6534-42
• All: 2 reference(s)