Fbl^em1Fuma
Endonuclease-mediated Allele Detail

Summary

• Symbol: Fbl^em1Fuma
• Name: fibrillarin; endonuclease-mediated mutation 1, Fumio Matsuzaki
• MGI ID: MGI:7260236
• Gene: Fbl Location: Chr7:27869135-27878694 bp, + strand Genetic Position: Chr7, 16.67 cM, cytoband A1
• Alliance: Fbl^em1Fuma page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• Mutation details: CRISPR/cas9 mediated recombination introduced a loxP site upstream of the firtst exon and a second loxP site downstream of the last exon. (J:322621)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fbl Mutation: 23 strains or lines available

References

• Original: J:322621 Wu Q, et al., Selective translation of epigenetic modifiers affects the temporal pattern and differentiation of neural stem cells. Nat Commun. 2022 Jan 25;13(1):470
• All: 1 reference(s)