Il2^tm1Weav
Targeted Allele Detail

Summary

• Symbol: Il2^tm1Weav
• Name: interleukin 2; targeted mutation 1, Casey T Weaver
• MGI ID: MGI:7258398
• Synonyms: IL-2.eGFP, IL2^{tm1(eGFP)Weav}
• Gene: Il2 Location: Chr3:37174862-37180103 bp, - strand Genetic Position: Chr3, 18.3 cM, cytoband B-C
• Alliance: Il2^tm1Weav page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:265346
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Reporter)
• Mutation: Insertion
• Mutation details: The targetign construct inserted into the fourth exon an IRES, EGFP reporter gene, and floxed neomycin resistance cassette. (J:265346)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Il2 Mutation: 32 strains or lines available

References

• Original: J:265346 DiToro D, et al., Differential IL-2 expression defines developmental fates of follicular versus nonfollicular helper T cells. Science. 2018 Sep 14;361(6407)
• All: 6 reference(s)