Ddah2^em1Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ddah2^em1Cya
• Name: DDAH family member 2, ADMA independent; endonuclease-mediated mutation 1, Cyagen Biosciences
• MGI ID: MGI:7258396
• Synonyms: Ddah2^em1Cgen, Ddah2^tm1cyagen
• Gene: Ddah2 Location: Chr17:35278011-35281071 bp, + strand Genetic Position: Chr17, 18.59 cM
• Alliance: Ddah2^em1Cya page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted exons 2 through 6. (J:320493)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ddah2 Mutation: 17 strains or lines available

References

• Original: J:320493 Xie Z, et al., Mechanical force promotes dimethylarginine dimethylaminohydrolase 1-mediated hydrolysis of the metabolite asymmetric dimethylarginine to enhance bone formation. Nat Commun. 2022 Jan 10;13(1):50
• All: 2 reference(s)