Manf^em1Jhe
Endonuclease-mediated Allele Detail

Summary

• Symbol: Manf^em1Jhe
• Name: mesencephalic astrocyte-derived neurotrophic factor; endonuclease-mediated mutation 1, Jinhan He
• MGI ID: MGI:7258395
• Synonyms: Manf^Loxp
• Gene: Manf Location: Chr9:106765952-106769137 bp, - strand Genetic Position: Chr9, 57.98 cM, cytoband F1
• Alliance: Manf^em1Jhe page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• Exon 2 was flanked by loxP sites using CRISPR/Cas9 technology. (J:322183)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Manf Mutation: 14 strains or lines available

References

• Original: J:322183 Wu T, et al., Feeding-induced hepatokine, Manf, ameliorates diet-induced obesity by promoting adipose browning via p38 MAPK pathway. J Exp Med. 2021 Jun 7;218(6)
• All: 2 reference(s)