Reep6^em3Ruch
Endonuclease-mediated Allele Detail

Summary

• Symbol: Reep6^em3Ruch
• Name: receptor accessory protein 6; endonuclease-mediated mutation 3, Rui Chen
• MGI ID: MGI:7258321
• Synonyms: Reep6^E5
• Gene: Reep6 Location: Chr10:80165831-80172275 bp, + strand Genetic Position: Chr10, 39.72 cM, cytoband C1
• Alliance: Reep6^em3Ruch page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Modified isoform(s))
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology deleted exon 5, generating a knock-out of the REEP6.1 isoform. (J:322326)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Reep6 Mutation: 19 strains or lines available

References

• Original: J:322326 Liang Q, et al., Transcript isoforms of Reep6 have distinct functions in the retina. Hum Mol Genet. 2021 Oct 13;30(21):1907-1918
• All: 1 reference(s)