Ephx2^em1Gpt
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ephx2^em1Gpt
• Name: epoxide hydrolase 2, cytoplasmic; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
• MGI ID: MGI:7258109
• Synonyms: Ephx2^em11Cd2615
• Gene: Ephx2 Location: Chr14:66321823-66361949 bp, - strand Genetic Position: Chr14, 34.36 cM, cytoband D
• Alliance: Ephx2^em1Gpt page

Mutation origin

• Strain of Origin: C57BL/6JGpt

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology deleted exons 4 and 5. (J:322262)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ephx2 Mutation: 40 strains or lines available

References

• Original: J:322262 Hu S, et al., Soluble Epoxide Hydrolase Deletion Attenuated Nicotine-induced Arterial Stiffness via Limiting the Loss of SIRT1. Am J Physiol Heart Circ Physiol. 2021 Jun 18
• All: 1 reference(s)