Dll1^em1Bip
Endonuclease-mediated Allele Detail

Summary

• Symbol: Dll1^em1Bip
• Name: delta like canonical Notch ligand 1; endonuclease-mediated mutation 1, Pengpeng Bi
• MGI ID: MGI:7256933
• Synonyms: Dll1^delta232
• Gene: Dll1 Location: Chr17:15587616-15597134 bp, - strand Genetic Position: Chr17, 8.95 cM
• Alliance: Dll1^em1Bip page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Modified regulatory region)
• Mutation: Intragenic deletion
• CRISPR/cas9 mediated recombination created a 232 bp deletion removing E box motifs in intron 4. (J:322147)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dll1 Mutation: 46 strains or lines available

References

• Original: J:322147 Zhang H, et al., Feedback regulation of Notch signaling and myogenesis connected by MyoD-Dll1 axis. PLoS Genet. 2021 Aug;17(8):e1009729
• All: 1 reference(s)