Ace2^em2(ACE2)Jrt
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ace2^em2(ACE2)Jrt
• Name: angiotensin converting enzyme 2; endonuclease-mediated mutation 2, Janet Rossant
• MGI ID: MGI:7256730
• Gene: Ace2 Location: ChrX:162922338-162971414 bp, + strand Genetic Position: ChrX, 76.12 cM, cytoband F5
• Alliance: Ace2^em2(ACE2)Jrt page

Mutation origin

• Strain of Origin: CD-1

Mutation description

• Allele Type: Endonuclease-mediated (Inserted expressed sequence, Null/knockout)
• Mutation: Insertion
• Ace2^em2(ACE2)Jrt expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  ACE2 (59272)

  Ace2	(MGI:1917258)

• Mutation details: CRISPR-targeting knockin a chimeric humanized ACE2 cDNA (human ECD and TM; mouse ICD and 3'UTR) at the ATG of mouse (J:322048)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Ace2 Mutation: 54 strains or lines available

References

• Original: J:322048 The Centre for Phenogenomics, Direct Data Submission for The Centre for Phenogenomics Alleles. MGI Direct Data Submission. 2022
• All: 1 reference(s)