Mir142^tm1.1Geno
Targeted Allele Detail

Summary

• Symbol: Mir142^tm1.1Geno
• Name: microRNA 142; targeted mutation 1.1, Genoway
• MGI ID: MGI:7256688
• Synonyms: Mir142^fl
• Gene: Mir142 Location: Chr11:87647690-87647753 bp, + strand Genetic Position: Chr11, 52.21 cM
• Alliance: Mir142^tm1.1Geno page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:321869
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: LoxP sites and an FRT-flanked neomycin resistance cassette were inserted to flank the locus. Flp-mediated recombination removed the selection cassette. (J:321869)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mir142 Mutation: 7 strains or lines available

References

• Original: J:321869 Anandagoda N, et al., Dominant regulation of long-term allograft survival is mediated by microRNA-142. Am J Transplant. 2020 Oct;20(10):2715-2727
• All: 2 reference(s)