Prdm1^em1Mbu
Endonuclease-mediated Allele Detail

Summary

• Symbol: Prdm1^em1Mbu
• Name: PR domain containing 1, with ZNF domain; endonuclease-mediated mutation 1, Meinrad Busslinger
• MGI ID: MGI:7256627
• Synonyms: Prdm1^delta3'U(90)
• Gene: Prdm1 Location: Chr10:44313173-44404497 bp, - strand Genetic Position: Chr10, 23.24 cM
• Alliance: Prdm1^em1Mbu page

Mutation origin

• Strain of Origin: Not Applicable

Mutation description

• Allele Type: Endonuclease-mediated (Not Applicable)
• Mutation: Intragenic deletion
• CRISRP-targeting deleted 2,253 bp of the 2,490 bp long 3UTR. (J:321896)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prdm1 Mutation: 69 strains or lines available

References

• Original: J:321896 Bonelt P, et al., Precocious expression of Blimp1 in B cells causes autoimmune disease with increased self-reactive plasma cells. EMBO J. 2019 Jan 15;38(2):e100010
• All: 1 reference(s)