Hnrnpd^tm1.1Dkon
Targeted Allele Detail

Summary

• Symbol: Hnrnpd^tm1.1Dkon
• Name: heterogeneous nuclear ribonucleoprotein D; targeted mutation 1.1, Dimitris L Kontoyiannis
• MGI ID: MGI:7256568
• Gene: Hnrnpd Location: Chr5:100103794-100126797 bp, - strand Genetic Position: Chr5, 48.46 cM, cytoband E3
• Alliance: Hnrnpd^tm1.1Dkon page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:321947
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: (C57BL/6 x 129)F1

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: The targeting cassette floxed exons 3 and 4 and inserted an FRT-flanked neomycin resistance cassette proximal to the exon 3 loxP site. Flp-mediated recombination removed the selection cassette. (J:321947)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Hnrnpd Mutation: 24 strains or lines available

References

• Original: J:321947 Gargani S, et al., Inactivation of AUF1 in Myeloid Cells Protects From Allergic Airway and Tumor Infiltration and Impairs the Adenosine-Induced Polarization of Pro-Angiogenic Macrophages. Front Immunol. 2022;13:752215
• All: 1 reference(s)