Ffar4^em1Jnu
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ffar4^em1Jnu
• Name: free fatty acid receptor 4; endonuclease-mediated mutation 1, Ji'nan University
• MGI ID: MGI:7256540
• Gene: Ffar4 Location: Chr19:38085527-38102711 bp, + strand Genetic Position: Chr19, 32.73 cM
• Alliance: Ffar4^em1Jnu page

Mutation origin

• Strain of Origin: Not Applicable

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology generated 26 bp and 7 bp deletions in the first exon. (J:325565)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ffar4 Mutation: 21 strains or lines available

References

• Original: J:325565 Zhu S, et al., Free fatty acid receptor 4 deletion attenuates colitis by modulating Treg Cells via ZBED6-IL33 pathway. EBioMedicine. 2022 Jun;80:104060
• All: 3 reference(s)