Tg(MMTV-CDC25B)4843Tsa
Transgene Detail

Summary

• Symbol: Tg(MMTV-CDC25B)4843Tsa
• Name: transgene insertion 4843, Sophia Y Tsai
• MGI ID: MGI:7254904
• Transgene: Tg(MMTV-CDC25B)4843Tsa Location: unknown
• Alliance: Tg(MMTV-CDC25B)4843Tsa page

Transgene origin

• Strain of Origin: ICR x (C57BL/6 x C3H)F1

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: This transgene consists of the mouse tumor virus (MMTV) promoter, a rabbit beta-globin gene fragment (KCR) comprising exon II, intron II, and exon III and poly(A) signal sequence, and the human CDC25B cDNA. This is a high expressing line. (J:174264)

Tumor Data

List all tumor models in MMHCdb carrying Tg(MMTV-CDC25B)4843Tsa

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:174264 Ma ZQ, et al., Induction of mammary gland hyperplasia in transgenic mice over-expressing human Cdc25B. Oncogene. 1999 Aug 12;18(32):4564-76
• All: 1 reference(s)