Tgfb1^em1Smoc
Endonuclease-mediated Allele Detail

Summary

• Symbol: Tgfb1^em1Smoc
• Name: transforming growth factor, beta 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
• MGI ID: MGI:6890383
• Synonyms: Tgfb1^{em1(flox)Smoc}, Tgfb1^f
• Gene: Tgfb1 Location: Chr7:25386427-25404502 bp, + strand Genetic Position: Chr7, 13.98 cM
• Alliance: Tgfb1^em1Smoc page

Mutation origin

• Strain of Origin: C57BL/6JSmoc

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• CRISPR-targeting floxed exon 2. (J:321367)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tgfb1 Mutation: 34 strains or lines available

References

• Original: J:321367 Gao L, et al., A resident stromal cell population actively restrains innate immune response in the propagation phase of colitis pathogenesis in mice. Sci Transl Med. 2021 Jul 21;13(603)
• All: 1 reference(s)