Gt(ROSA)26Sor^{tm1(CAG-Mep1b)Chbe}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm1(CAG-Mep1b)Chbe}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Christoph Becker
• MGI ID: MGI:6888290
• Synonyms: Rosa26^Mep1b-HA
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm1(CAG-Mep1b)Chbe} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:321387
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Conditional ready, Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: The targeting mutation inserted into the locus a CAG promoter, floxed stop/selection cassette, and murine cDNA with an HA-tag. (J:321387)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1089 strains or lines available

References

• Original: J:321387 Peters F, et al., Syndecan-1 shedding by meprin beta impairs keratinocyte adhesion and differentiation in hyperkeratosis. Matrix Biol. 2021 Aug;102:37-69
• All: 1 reference(s)