Ccr3^tm1Vlcg
Targeted Allele Detail

Summary

• Symbol: Ccr3^tm1Vlcg
• Name: C-C motif chemokine receptor 3; targeted mutation 1, Velocigene
• MGI ID: MGI:6888173
• Gene: Ccr3 Location: Chr9:123822009-123831726 bp, + strand Genetic Position: Chr9, 75.05 cM, cytoband F
• Alliance: Ccr3^tm1Vlcg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:102034
• Parent Cell Line: CJ7 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The targeting construct replaced 1074 bp of the coding region, including exon 2, with a lacZ reporter gene and neomycin resistance cassette. (J:102034)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ccr3 Mutation: 31 strains or lines available

References

• Original: J:102034 Pope SM, et al., The eotaxin chemokines and CCR3 are fundamental regulators of allergen-induced pulmonary eosinophilia. J Immunol. 2005 Oct 15;175(8):5341-50
• All: 2 reference(s)