Tlr2^em1Smoc
Endonuclease-mediated Allele Detail

Summary

• Symbol: Tlr2^em1Smoc
• Name: toll-like receptor 2; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
• MGI ID: MGI:6888153
• Gene: Tlr2 Location: Chr3:83743579-83749045 bp, - strand Genetic Position: Chr3, 37.4 cM
• Alliance: Tlr2^em1Smoc page

Mutation origin

• Strain of Origin: C57BL/6JSmoc

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted exon 3. (J:321705)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Tlr2 Mutation: 61 strains or lines available

References

• Original: J:321705 Xu Y, et al., Induction of Foxp3 and activation of Tregs by HSP gp96 for treatment of autoimmune diseases. iScience. 2021 Dec 17;24(12):103445
• All: 3 reference(s)