Bckdhb^m1
Spontaneous Allele Detail

Summary

• Symbol: Bckdhb^m1
• Name: branched chain ketoacid dehydrogenase E1, beta polypeptide; mutation 1
• MGI ID: MGI:6888017
• Gene: Bckdhb Location: Chr9:83807198-84006293 bp, + strand Genetic Position: Chr9, 45.67 cM
• Alliance: Bckdhb^m1 page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Spontaneous (Hypomorph)
• Mutation: Insertion
• Mutation details: The allele contains an LTR retrotransposon insertion in intron 1 (IAPLTR1_Mn) that reduces transcript expression in C57BL/6J mice compared with 129S2/SvPasCrl and DBA/2J. (J:321710)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bckdhb Mutation: 21 strains or lines available

References

• Original: J:321710 Leandro J, et al., Mild inborn errors of metabolism in commonly used inbred mouse strains. Mol Genet Metab. 2019;126(4):388-396
• All: 1 reference(s)