Ace2^em6Lutzy
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ace2^em6Lutzy
• Name: angiotensin converting enzyme 2; endonuclease-mediated mutation 6, Cathy Lutz
• MGI ID: MGI:6886055
• Synonyms: Ace2^del1G
• Gene: Ace2 Location: ChrX:162922338-162971414 bp, + strand Genetic Position: ChrX, 76.12 cM, cytoband F5
• Alliance: Ace2^em6Lutzy page

Mutation origin

• Strain of Origin: B6.Cg-Fcgrt^tm1Dcr Tg(FCGRT)32Dcr/DcrJ

Mutation description

• Allele Type: Endonuclease-mediated (Not Specified)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/cas9 genome editing generated a 1 nt frameshift deletion (indel mutation) that starts at amino acid 352 (ACAGCTTGGGATCTGG//del1G//ACACGGAGACTTCAG). (J:101977)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ace2 Mutation: 72 strains or lines available

References

• Original: J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017
• All: 1 reference(s)