Zdbf2^em4Dhbh
Endonuclease-mediated Allele Detail

Summary

• Symbol: Zdbf2^em4Dhbh
• Name: zinc finger, DBF-type containing 2; endonuclease-mediated mutation 4, Deborah Bourchis
• MGI ID: MGI:6885949
• Synonyms: Liz_379, Zdbf2-GOF
• Gene: Zdbf2 Location: Chr1:63312424-63353735 bp, + strand Genetic Position: Chr1, 32.31 cM, cytoband C2
• Alliance: Zdbf2^em4Dhbh page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Modified isoform(s), Modified regulatory region)
• Mutations: Intergenic deletion, Intragenic deletion
• Mutation details: CRISPR-targeting deleted 924 bp (chr1:63,199,369-63,200,292 GRCm38) spanning a 5' part of germline differentially methylated region (gDMR, Rr188), including a 5' part of the first exon of the long coding isoform, in intron 2 of Gpr1. (J:319657)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Zdbf2 Mutation: 102 strains or lines available

References

• Original: J:319657 Glaser J, et al., The imprinted Zdbf2 gene finely tunes control of feeding and growth in neonates. Elife. 2022 Jan 20;11:e65641
• All: 1 reference(s)