Zdbf2^em3Dhbh
Endonuclease-mediated Allele Detail

Summary

• Symbol: Zdbf2^em3Dhbh
• Name: zinc finger, DBF-type containing 2; endonuclease-mediated mutation 3, Deborah Bourchis
• MGI ID: MGI:6885918
• Synonyms: deltagDMR, deltaLiz, Line 393
• Gene: Zdbf2 Location: Chr1:63312424-63353735 bp, + strand Genetic Position: Chr1, 32.31 cM, cytoband C2
• Alliance: Zdbf2^em3Dhbh page

Mutation origin

• Strain of Origin: (C57BL/6J X DBA/2)F2

Mutation description

• Allele Type: Endonuclease-mediated (Not Applicable)
• Mutation: Intragenic deletion
• Mutation details: CRISPR-targeting deleted 1715 bp (chr1:63,199,617-63,201,331 GRCm38) spanning the germline differentially methylated region (gDMR, Rr188), including the first exon of the long coding isoform, in intron 2 of Gpr1. (J:261327)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Zdbf2 Mutation: 102 strains or lines available

References

• Original: J:261327 Greenberg MV, et al., Transient transcription in the early embryo sets an epigenetic state that programs postnatal growth. Nat Genet. 2017 Jan;49(1):110-118
• All: 1 reference(s)