Copb2^em1Brle
Endonuclease-mediated Allele Detail

Summary

• Symbol: Copb2^em1Brle
• Name: COPI coat complex subunit beta 2; endonuclease-mediated mutation 1, Brendan Lee
• MGI ID: MGI:6885780
• Gene: Copb2 Location: Chr9:98445784-98470428 bp, + strand Genetic Position: Chr9, 51.4 cM, cytoband E3-F1
• Alliance: Copb2^em1Brle page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology deleted exons 6 and 7. (J:321261)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Copb2 Mutation: 27 strains or lines available

References

• Original: J:321261 Marom R, et al., COPB2 loss of function causes a coatopathy with osteoporosis and developmental delay. Am J Hum Genet. 2021 Sep 2;108(9):1710-1724
• All: 1 reference(s)