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Endonuclease-mediated Allele Detail
Symbol: Adcy5em2Lutzy
Name: adenylate cyclase 5; endonuclease-mediated mutation 2, Cathleen Lutz
MGI ID: MGI:6879499
Synonyms: Adcy5A727T
Gene: Adcy5  Location: Chr16:34975247-35126108 bp, + strand  Genetic Position: Chr16, 24.71 cM, cytoband B-5
Alliance: Adcy5em2Lutzy page
Strain of Origin:  C57BL/6J
Allele Type:    Endonuclease-mediated (Not Specified)
Mutation:    Nucleotide substitutions
Mutation detailsCRISPR/cas9 genome editing used guide RNAs (TGGGTCGGGCCATCGATGCC and TCGCAGTCTGTCGATGCTCC) to target exon 10. Donor DNAs were created encoding a A727T mutation (GCC to ACA, alanine to threonine). (J:94077)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Adcy5 Mutation:  37 strains or lines available
Original:  J:94077 Mutant Mouse Regional Resource Centers, Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC). Unpublished. 2004-2015;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
MGI 6.22
The Jackson Laboratory