Dpt^em1Lunt
Endonuclease-mediated Allele Detail

Summary

• Symbol: Dpt^em1Lunt
• Name: dermatopontin; endonuclease-mediated mutation 1, Troy C Lund
• MGI ID: MGI:6872324
• Gene: Dpt Location: Chr1:164624232-164651843 bp, + strand Genetic Position: Chr1, 72.12 cM, cytoband H2
• Alliance: Dpt^em1Lunt page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR-mediated recombination created a 50 bp deletion in exon 1 creating a frameshift and multiple down stream stop codons. (J:320397)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dpt Mutation: 16 strains or lines available

References

• Original: J:320397 Kramer AC, et al., Dermatopontin in Bone Marrow Extracellular Matrix Regulates Adherence but Is Dispensable for Murine Hematopoietic Cell Maintenance. Stem Cell Reports. 2017 Sep 12;9(3):770-778
• All: 1 reference(s)