G2e3^{Gt(OSTGST3673G2)Lex}
Gene trapped Allele Detail

Summary

• Symbol: G2e3^{Gt(OSTGST3673G2)Lex}
• Name: G2/M-phase specific E3 ubiquitin ligase; gene trap OSTGST3673G2, Lexicon Genetics
• MGI ID: MGI:6872309
• Gene: G2e3 Location: Chr12:51395013-51423769 bp, + strand Genetic Position: Chr12, 22.11 cM
• Alliance: G2e3^{Gt(OSTGST3673G2)Lex} page

Mutation origin

• Mutant Cell Line: OSTGST3673G2
• Germline Transmission: Earliest citation of germline transmission: J:320342
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• The beta-geo containing gene trap inserted into intron 1. (J:320342)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any G2e3 Mutation: 38 strains or lines available

References

• Original: J:320342 Powell DR, et al., Obesity of G2e3 Knockout Mice Suggests That Obesity-Associated Variants Near Human G2E3 Decrease G2E3 Activity. Diabetes Metab Syndr Obes. 2020;13:2641-2652
• All: 1 reference(s)