Efl1^em1Snu
Endonuclease-mediated Allele Detail

Summary

• Symbol: Efl1^em1Snu
• Name: elongation factor like GTPase 1; endonuclease-mediated mutation 1, Seoul National University
• MGI ID: MGI:6871049
• Gene: Efl1 Location: Chr7:82297822-82427060 bp, + strand Genetic Position: Chr7, 47.25 cM
• Alliance: Efl1^em1Snu page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting of exon 10 deleted 10 bp. (J:315678)

Expression

In Mice Carrying this Mutation:

12 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Efl1 Mutation: 57 strains or lines available

References

• Original: J:315678 Lee S, et al., Somatic uniparental disomy mitigates the most damaging EFL1 allele combination in Shwachman-Diamond syndrome. Blood. 2021 Nov 25;138(21):2117-2128
• All: 1 reference(s)