Runx2^tm1.1Arte
Targeted Allele Detail

Summary

• Symbol: Runx2^tm1.1Arte
• Name: runt related transcription factor 2; targeted mutation 1.1, TaconicArtemis
• MGI ID: MGI:6867838
• Synonyms: Runx2^f
• Gene: Runx2 Location: Chr17:44806873-45125518 bp, - strand Genetic Position: Chr17, 21.33 cM
• Alliance: Runx2^tm1.1Arte page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:318811
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• The targeting construct floxed exon 4. Flp-mediated recombination removed the selection cassette. (J:318811)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Runx2 Mutation: 45 strains or lines available

References

• Original: J:318811 Cobb AM, et al., Runx2 (Runt-Related Transcription Factor 2) Links the DNA Damage Response to Osteogenic Reprogramming and Apoptosis of Vascular Smooth Muscle Cells. Arterioscler Thromb Vasc Biol. 2021 Apr;41(4):1339-1357
• All: 1 reference(s)