Akap3^em1Hqi
Endonuclease-mediated Allele Detail

Summary

• Symbol: Akap3^em1Hqi
• Name: A kinase anchor protein 3; endonuclease-mediated mutation 1, Huayu Qi
• MGI ID: MGI:6867043
• Gene: Akap3 Location: Chr6:126830061-126851271 bp, + strand Genetic Position: Chr6, 61.92 cM
• Alliance: Akap3^em1Hqi page

Mutation origin

• Strain of Origin: Not Applicable

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting of the fifth exon deleted 103 bp, resulting in a frameshift. (J:284173)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Akap3 Mutation: 32 strains or lines available

References

• Original: J:284173 Xu K, et al., Lack of AKAP3 disrupts integrity of the subcellular structure and proteome of mouse sperm and causes male sterility. Development. 2020 Jan 22;147(2):dev181057
• All: 1 reference(s)