Pabpc2^tm1Tba
Targeted Allele Detail

Summary

• Symbol: Pabpc2^tm1Tba
• Name: poly(A) binding protein, cytoplasmic 2; targeted mutation 1, Tadashi Baba
• MGI ID: MGI:6867024
• Gene: Pabpc2 Location: Chr18:39906550-39909135 bp, + strand Genetic Position: Chr18, 21.14 cM
• Alliance: Pabpc2^tm1Tba page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:319556
• Parent Cell Line: D3 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• The targeting construct replaced part of the coding sequence with a neomycin resistance cassette. (J:319556)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pabpc2 Mutation: 31 strains or lines available

References

• Original: J:319556 Kashiwabara S, et al., Functional compensation for the loss of testis-specific poly(A)-binding protein, PABPC2, during mouse spermatogenesis. J Reprod Dev. 2016 Jun 17;62(3):305-10
• All: 1 reference(s)