Slc25a39^em1Brsy
Endonuclease-mediated Allele Detail

Summary

• Symbol: Slc25a39^em1Brsy
• Name: solute carrier family 25, member 39; endonuclease-mediated mutation 1, Kivanc Birsoy
• MGI ID: MGI:6867019
• Gene: Slc25a39 Location: Chr11:102293811-102298772 bp, - strand Genetic Position: Chr11, 66.29 cM, cytoband D
• Alliance: Slc25a39^em1Brsy page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR-mediated recombination created an approximately 700 bp deletion removing a genomic region including all of exons 2 and 3. (J:319863)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc25a39 Mutation: 30 strains or lines available

References

• Original: J:319863 Wang Y, et al., SLC25A39 is necessary for mitochondrial glutathione import in mammalian cells. Nature. 2021 Nov;599(7883):136-140
• All: 1 reference(s)