Pink1^em1Smoc
Endonuclease-mediated Allele Detail

Summary

• Symbol: Pink1^em1Smoc
• Name: PTEN induced putative kinase 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
• MGI ID: MGI:6865741
• Gene: Pink1 Location: Chr4:138040720-138053618 bp, - strand Genetic Position: Chr4, 70.14 cM
• Alliance: Pink1^em1Smoc page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting deleted exons 2 through 4. (J:319499)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Pink1 Mutation: 42 strains or lines available

References

• Original: J:319499 Huang T, et al., Fbxo7 and Pink1 play a reciprocal role in regulating their protein levels. Aging (Albany NY). 2020 Dec 3;13(1):77-88
• All: 1 reference(s)