Trib1^tm1.1Tanak
Targeted Allele Detail

Summary

• Symbol: Trib1^tm1.1Tanak
• Name: tribbles pseudokinase 1; targeted mutation 1.1, Takuro Nakamura
• MGI ID: MGI:6865734
• Synonyms: Trib1^ko
• Gene: Trib1 Location: Chr15:59520503-59528948 bp, + strand Genetic Position: Chr15, 25.41 cM
• Alliance: Trib1^tm1.1Tanak page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:303716
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: LoxP sites were inserted in intron 1 and at 325 bp downstream of exon 3. Exons 2-3 were removed via cre-mediated recombination in the germline. (J:303716)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Trib1 Mutation: 24 strains or lines available

References

• Original: J:303716 Yoshino S, et al., Trib1 promotes acute myeloid leukemia progression by modulating the transcriptional programs of Hoxa9. Blood. 2021 Jan 7;137(1):75-88
• All: 1 reference(s)