Ccnd2^em1Vic
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ccnd2^em1Vic
• Name: cyclin D2; endonuclease-mediated mutation 1, Gabriel Victora
• MGI ID: MGI:6864287
• Gene: Ccnd2 Location: Chr6:127102125-127129156 bp, - strand Genetic Position: Chr6, 61.92 cM
• Alliance: Ccnd2^em1Vic page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 technology generated a 4-bp deletion in exon 1 resulting in a frameshift. (J:307801)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ccnd2 Mutation: 26 strains or lines available

References

• Original: J:307801 Pae J, et al., Cyclin D3 drives inertial cell cycling in dark zone germinal center B cells. J Exp Med. 2021 Apr 5;218(4)
• All: 1 reference(s)