Il27^tm1Doe
Targeted Allele Detail

Summary

• Symbol: Il27^tm1Doe
• Name: interleukin 27; targeted mutation 1, Thomas Doetschman
• MGI ID: MGI:6864281
• Synonyms: IL-27p28^-, IL30^-, IL-30 (p28)^-
• Gene: Il27 Location: Chr7:126188182-126194113 bp, - strand Genetic Position: Chr7, 69.18 cM
• Alliance: Il27^tm1Doe page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:273496
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A loxP-flanked neomycin resistance cassette replaced exons 1-5. (J:273496)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Il27 Mutation: 23 strains or lines available

References

• Original: J:273496 Yan J, et al., Interleukin-30 (IL27p28) alleviates experimental sepsis by modulating cytokine profile in NKT cells. J Hepatol. 2016 May;64(5):1128-1136
• All: 2 reference(s)