Arrb2^tm1Jklw
Targeted Allele Detail

Summary

• Symbol: Arrb2^tm1Jklw
• Name: arrestin, beta 2; targeted mutation 1, Julia KL Walker
• MGI ID: MGI:6864273
• Synonyms: Betaarr2^flx
• Gene: Arrb2 Location: Chr11:70323461-70331654 bp, + strand Genetic Position: Chr11, 42.99 cM
• Alliance: Arrb2^tm1Jklw page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:291304
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Exon 2 was flanked by loxP sites. (J:291304)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Arrb2 Mutation: 28 strains or lines available

References

• Original: J:291304 Chen M, et al., Genetic Deletion of beta-Arrestin-2 and the Mitigation of Established Airway Hyperresponsiveness in a Murine Asthma Model. Am J Respir Cell Mol Biol. 2015 Sep;53(3):346-54
• All: 6 reference(s)