Map3k1^m1Yzcm
Chemically induced Allele Detail

Summary

• Symbol: Map3k1^m1Yzcm
• Name: mitogen-activated protein kinase kinase kinase 1; mutation 1, Yangzhou University Comparative Medicine Center
• MGI ID: MGI:6860635
• Synonyms: Map3k1^L314Q
• Gene: Map3k1 Location: Chr13:111882962-111945527 bp, - strand Genetic Position: Chr13, 63.36 cM
• Alliance: Map3k1^m1Yzcm page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a T to A point mutation that resulted in the amino acid substitution of leucine for glutamine at position 314 (L314Q). (J:318638)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Map3k1 Mutation: 63 strains or lines available

References

• Original: J:318638 Chen B, et al., An L314Q mutation in Map3k1 gene results in failure of eyelid fusion in the N-ethyl-N-nitrosourea-induced mutant line. Exp Anim. 2021;70(4):459-468
• All: 1 reference(s)