Rragd^em1Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rragd^em1Cya
• Name: Ras-related GTP binding D; endonuclease-mediated mutation 1, Cyagen Biosciences
• MGI ID: MGI:6860363
• Synonyms: Rragd^em1Cgen, Rragd^fl
• Gene: Rragd Location: Chr4:32983037-33022180 bp, + strand Genetic Position: Chr4, 14.57 cM
• Alliance: Rragd^em1Cya page

Mutation origin

• Strain of Origin: C57BL/6JGpt

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• CRISPR-targeting flanked exon 2 through 4. (J:317433)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rragd Mutation: 23 strains or lines available

References

• Original: J:317433 Zhang Y, et al., Amino acids and RagD potentiate mTORC1 activation in CD8(+) T cells to confer antitumor immunity. J Immunother Cancer. 2021 Apr;9(4)
• All: 1 reference(s)