Rpl39l^em1Hqi
Endonuclease-mediated Allele Detail

Summary

• Symbol: Rpl39l^em1Hqi
• Name: ribosomal protein L39-like; endonuclease-mediated mutation 1, Huayu Qi
• MGI ID: MGI:6857773
• Gene: Rpl39l Location: Chr16:9988090-9992775 bp, + strand Genetic Position: Chr16, 5.49 cM, cytoband A3
• Alliance: Rpl39l^em1Hqi page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Insertion
• Mutation details: CRISPR/Cas9 technology generated a 19-bp insertion near the start codon in exon 3 causing a frameshift near the starting codon. No off-targeting mutations were found. (J:317811)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rpl39l Mutation: 4 strains or lines available

References

• Original: J:317811 Zou Q, et al., Proteostasis regulated by testis-specific ribosomal protein RPL39L maintains mouse spermatogenesis. iScience. 2021 Dec 17;24(12):103396
• All: 1 reference(s)