Cd274^{tm1.1(CD274)Geno}
Targeted Allele Detail

Summary

• Symbol: Cd274^{tm1.1(CD274)Geno}
• Name: CD274 antigen; targeted mutation 1.1, Genoway
• MGI ID: MGI:6857639
• Gene: Cd274 Location: Chr19:29344855-29365495 bp, + strand Genetic Position: Chr19, 23.88 cM, cytoband C2
• Alliance: Cd274^{tm1.1(CD274)Geno} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:317752
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Inserted expressed sequence, Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Cd274^{tm1.1(CD274)Geno} expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  CD274 (29126)

  Cd274

  (MGI:1926446)

• Mutation details: The chimeric allele encodes an ENTPD1 protein with the human extracellular and mouse transmembrane and intracellular domains. The final allele lacks the self-excising selection cassette. (J:317752)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cd274 Mutation: 71 strains or lines available

References

• Original: J:317752 Bertaux F, Direct Data Submission for Knock-in Genoway Alleles. MGI Direct Data Submission. 2022
• All: 1 reference(s)