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Tg(Rr139-lacZ)#Makm
Transgene Detail
Summary
Symbol: Tg(Rr139-lacZ)#Makm
Name: transgene insertion, Marie Kmita
MGI ID: MGI:6856857
Synonyms: Tg(m-Inta11-LacZ)
Transgene: Tg(Rr139-lacZ)#Makm  Location: unknown  
Alliance: Tg(Rr139-lacZ)#Makm page
Transgene
origin
Strain of Origin:  Not Applicable
Transgene
description
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
 
Mutation detailsSequence from intron 1 of Hoxa11, containing distal or digit enhancer Rr139, was cloned upstream of the hemoglobin beta minimal promoter to drive expression of the beta-galactosidase reporter gene (LacZdeltaCpG NLS). The H19 insulator Rr27 was placed upstream of Rr139 to block any putative interaction with enhancers around the insertion site. (J:239414)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:239414 Kherdjemil Y, et al., Evolution of Hoxa11 regulation in vertebrates is linked to the pentadactyl state. Nature. 2016 Nov 03;539(7627):89-92
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/20/2026
MGI 6.24
The Jackson Laboratory