Pabpn1l^em1Mlx
Endonuclease-mediated Allele Detail

Summary

• Symbol: Pabpn1l^em1Mlx
• Name: poly(A)binding protein nuclear 1-like; endonuclease-mediated mutation 1, Mingxi Liu
• MGI ID: MGI:6856829
• Gene: Pabpn1l Location: Chr8:123346210-123349474 bp, - strand Genetic Position: Chr8, 71.93 cM
• Alliance: Pabpn1l^em1Mlx page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR-targeting of intron 1 to exon 2 deleted 41 bp and produced a null allele. (J:317402)

Expression

In Mice Carrying this Mutation:

3 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pabpn1l Mutation: 11 strains or lines available

References

• Original: J:317402 Wang Y, et al., PABPN1L assemble into "ring-like" aggregates in the cytoplasm of MII oocytes and is associated with female infertility. Biol Reprod. 2022 Jan 13;106(1):83-94
• All: 1 reference(s)