Nrip2^em1Cya
Endonuclease-mediated Allele Detail

Summary

• Symbol: Nrip2^em1Cya
• Name: nuclear receptor interacting protein 2; endonuclease-mediated mutation 1, Cyagen Biosciences
• MGI ID: MGI:6856803
• Synonyms: Nrip2^em1Cgen, Nrip2 KO
• Gene: Nrip2 Location: Chr6:128374780-128386747 bp, + strand Genetic Position: Chr6, 62.99 cM, cytoband F3
• Alliance: Nrip2^em1Cya page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Deletion
• Mutation details: The exons 2-4 were deleted using the CRISPR/Cas9 system. Loss of Nrip2 protein product was confirmed by western blotting (WB) of kidney cortices. (J:317698)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nrip2 Mutation: 16 strains or lines available

References

• Original: J:317698 Hou Q, et al., Nuclear Receptor Interacting Protein-2 Mediates the Stabilization and Activation of beta-Catenin During Podocyte Injury. Front Cell Dev Biol. 2021;9:781792
• All: 1 reference(s)