Hars2^em1Gpt
Endonuclease-mediated Allele Detail

Summary

• Symbol: Hars2^em1Gpt
• Name: histidyl-tRNA synthetase 2; endonuclease-mediated mutation 1, GemPharmatech Co., Ltd
• MGI ID: MGI:6856802
• Synonyms: Hars2^Loxp
• Gene: Hars2 Location: Chr18:36916257-36925615 bp, + strand Genetic Position: Chr18, 19.46 cM
• Alliance: Hars2^em1Gpt page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• Exons 1 to 8 were flanked by loxP sites using CRISPR/Cas9 technology. (J:317697)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hars2 Mutation: 31 strains or lines available

References

• Original: J:317697 Xu P, et al., Disruption of Hars2 in Cochlear Hair Cells Causes Progressive Mitochondrial Dysfunction and Hearing Loss in Mice. Front Cell Neurosci. 2021;15:804345
• All: 1 reference(s)