Tmprss2^{em1(TMPRSS2)Mbp}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Tmprss2^{em1(TMPRSS2)Mbp}
• Name: transmembrane protease, serine 2; endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
• MGI ID: MGI:6856764
• Gene: Tmprss2 Location: Chr16:97365882-97412395 bp, - strand Genetic Position: Chr16, 57.53 cM, cytoband C2
• Alliance: Tmprss2^{em1(TMPRSS2)Mbp} page

Mutation origin

• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Endonuclease-mediated (Inserted expressed sequence)
• Mutations: Insertion, Intragenic deletion
• Tmprss2^{em1(TMPRSS2)Mbp} expresses 1 gene
  Knock-in expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  TMPRSS2 (7113)

  Tmprss2

  (MGI:1354381)

• Mutation details: CRISPR-targeting inserted exons 3-14 of the human sequence (ENSG00000184012.14) in-frame into exon 2 and removed the mouse exon 2 splice acceptor and the guide protospacer (nt 1-17). (J:94077)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 3 strains available Cell Lines: 0 lines available
• Carrying any Tmprss2 Mutation: 46 strains or lines available

References

• Original: J:94077 Mutant Mouse Regional Resource Centers, Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC). Unpublished. 2004-2015
• All: 1 reference(s)