Gt(ROSA)26Sor^{tm1(Fabp5)Galf}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm1(Fabp5)Galf}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Fabienne Gally
• MGI ID: MGI:6856507
• Synonyms: FABP5-Tg, Rosa26-STOPflox-Fabp5-2A-YFP
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm1(Fabp5)Galf} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:317465
• Parent Cell Line: JM8A3 (ES Cell)
• Strain of Origin: C57BL/6N-A^tm1Brd

Mutation description

• Allele Type: Targeted (Conditional ready, Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Gt(ROSA)26Sor^{tm1(Fabp5)Galf} expresses 1 gene
  Knock-in expresses:
  

  Organism	Expressed Gene	Note
  mouse	Fabp5 (MGI:101790)

• Mutation details: The targeting vector contains from 5' to 3' a loxP site, a STOP cassette containing a neomycin resistance gene followed by a second loxP site, the murine Fabp5 cDNA, a viral 2A oligopeptide (T2A) self cleaving peptide (which mediates ribosomal skipping), and a yellow fluorescent protein (YFP) reporter, and a polyadenylation sequence. (J:317465)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 944 strains or lines available

References

• Original: J:317465 Rao DM, et al., Mice Lacking Fatty Acid-Binding Protein 5 Are Resistant to Listeria monocytogenes. J Innate Immun. 2019;11(6):469-480
• All: 1 reference(s)