Gt(ROSA)26Sor^{em1(CAG-SCNN1D/EGFP)Hoji}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{em1(CAG-SCNN1D/EGFP)Hoji}
• Name: gene trap ROSA 26, Philippe Soriano; endonuclease-mediated mutation 1, Ji Honglong
• MGI ID: MGI:6852748
• Synonyms: Delta^802Tg
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{em1(CAG-SCNN1D/EGFP)Hoji} page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: CRISPR-targeting inserted into the locus a CAG promoter, FRT site, floxed stop cassette, the full-length human sequence encoding the 802 amino acid protein with HA and His tags and fused to the EGFP reporter gene, polyadenylation sequence, AttB, FRT site, neomycin resistance cassette, polyadenylation sequence, and AttP site. (J:317190)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1089 strains or lines available

References

• Original: J:317190 Zhao R, et al., Proliferative regulation of alveolar epithelial type 2 progenitor cells by human Scnn1d gene. Theranostics. 2019;9(26):8155-8170
• All: 1 reference(s)