Tg(Rho-Sag*F86A*F198A)175Seva
Transgene Detail

Summary

• Symbol: Tg(Rho-Sag*F86A*F198A)175Seva
• Name: transgene insertion 175, Vsevolod Gurevich
• MGI ID: MGI:6852586
• Synonyms: CM175, Tg(Rho-Sag*F86A,F198A)175Seva
• Transgene: Tg(Rho-Sag*F86A*F198A)175Seva Location: unknown
• Alliance: Tg(Rho-Sag*F86A*F198A)175Seva page

Transgene origin

• Strain of Origin: (C57BL/6J x DBA/2J)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Rho-Sag*F86A*F198A)175Seva expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Sag (MGI:98227)	mutations F86A;F198A

• Mutation details: The transgene contains the mouse promoter driving retinal expression of the mouse cDNA with the mutations of phenylalanine to alanine at position 86 and 198 (F86A, F198A). Line 175 expresses at 175% of wild-type level. (J:296598)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:296598 Samaranayake S, et al., Biological Role of Arrestin-1 Oligomerization. J Neurosci. 2020 Oct 14;40(42):8055-8069
• All: 1 reference(s)