Tlr2^tm1.1Stplz
Targeted Allele Detail

Summary

• Symbol: Tlr2^tm1.1Stplz
• Name: toll-like receptor 2; targeted mutation 1.1, Laura Schuettpelz
• MGI ID: MGI:6852544
• Synonyms: Tlr2 flx
• Gene: Tlr2 Location: Chr3:83743579-83749045 bp, - strand Genetic Position: Chr3, 37.4 cM
• Alliance: Tlr2^tm1.1Stplz page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:101977
• Parent Cell Line: iTL HF4 (ES Cell)
• Strain of Origin: 129S/SvEv x C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: The targeting vector is designed to insert a loxP- and FRT-flanked neomycin resistance cassette upstream of exon 3 and a third loxP site was inserted downstream of exon 3. Flp-mediated recombination removed the neomycin cassette. (J:101977)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Tlr2 Mutation: 61 strains or lines available

References

• Original: J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017
• All: 2 reference(s)