Gt(ROSA)26Sor^{em1(CAG-cas9)Jdd}
Endonuclease-mediated Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{em1(CAG-cas9)Jdd}
• Name: gene trap ROSA 26, Philippe Soriano; endonuclease-mediated mutation 1, Joseph D Dougherty
• MGI ID: MGI:6850668
• Synonyms: LSL-Rosa26 Cag Cas9
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{em1(CAG-cas9)Jdd} page

Mutation origin

• Strain of Origin: (C57BL/6 x CBA)F1

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, Endonuclease, No functional change)
• Mutation: Insertion
• Mutation details: TALEN-targeting with a donor plasmid inserted a CAG enhancer, Lox-Stop-Lox cassette, and a triple Flag-NLS-Cas9-NLS. (J:94077)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 1058 strains or lines available

References

• Original: J:94077 Mutant Mouse Regional Resource Centers, Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC). Unpublished. 2004-2015
• All: 2 reference(s)